This month in Eyes on Evidence
Prescribing safety in UK general practice
A cross-sectional study of patients from more than 500 UK general practices found high variation in potentially high-risk prescribing and provision of monitoring tests.
Drug efficacy in older people with multimorbidity
A US cohort study found that warfarin, beta-blockers, calcium channel blockers, renin–angiotensin system blockers, statins and thiazides reduced mortality when used for an indicated condition in older people with multimorbidity.
Testosterone preparations for men with hypogonadism
A cohort study of US and UK data found that men who used testosterone injections were at higher risk of cardiovascular events, death and hospitalisation than men who used testosterone gels, although the absolute risks were small.
Clinical outcomes in people with obstructive sleep apnoea
A large cohort study in the USA reported that both treated and untreated obstructive sleep apnoea were associated with an increased risk of death and of developing coronary heart disease, stroke or kidney dysfunction.
Older people’s views on advance care planning
A survey in the east midlands found that only 5% of people aged 65 years or older had been offered an opportunity to talk about advance care planning by a health or social care professional, although around a third said they would be interested in discussing the topic.
Evidence summaries from NICE’s Medicines and Prescribing Programme
NICE has recently published summaries on:
- Prevention of chemotherapy induced nausea and vomiting in adults: netupitant/palonosetron
- Hypertension in adults: intensive or standard blood-pressure control?
- Chronic obstructive pulmonary disease: comparative safety and efficacy of long-acting inhaled agents
- Psychotropic drug prescribing for people with learning disabilities
- Medication underuse in older people: pharmaceutical care interventions
- Medicines optimisation: key therapeutic topics (2016 update)
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