This month in Eyes on Evidence...
Quality of life in young people with cerebral palsy
A study of cross-sectional and longitudinal European data found that young people with mild or moderate cerebral palsy mostly had similar quality of life to young people in the general population, but had less social support from friends and peers.
Fractional flow reserve to guide percutaneous coronary intervention in people with stable coronary artery disease
An international multicentre randomised controlled trial reported that people with stable coronary artery disease who had significant stenosis according to fractional flow reserve values had better outcomes with percutaneous coronary intervention plus medical therapy than with medical therapy alone.
Latanoprost for newly diagnosed open-angle glaucoma
A randomised controlled trial found that, in people with newly diagnosed open-angle glaucoma, latanoprost eye drops significantly increased the time to visual field deterioration within 24 months compared with placebo eye drops.
Childhood factors and inactivity in adulthood
A British cohort study found that a number of physical, social and behavioural factors in childhood – such as height, social status and conduct problems – were associated with low physical activity in adulthood.
‘Positive’ and ‘negative’ emotive content in tobacco control TV adverts
A UK study reported that ‘positive’ televised tobacco control adverts increased the rate of calls per month to the NHS Stop Smoking quitline in line with how often the adverts were aired, whereas ‘negative’ campaigns increased the rate of calls only once exposure exceeded a certain threshold.
Evidence summaries from NICE’s Medicines and Prescribing Programme
NICE has recently published medicines evidence summaries on:
- Type 2 diabetes: insulin degludec/liraglutide (Xultophy)
- Type 2 diabetes: dulaglutide (Trulicity)
- Ulcerative colitis: budesonide multimatrix (Cortiment)
- Acute coronary syndrome: ezetimibe added to simvastatin (IMPROVE-IT study)
- Gastrointestinal bleeding: differences among anticoagulants
- Cardiovascular disease: risk of diabetes and statin treatment
- Risk of suicide, attempted suicide or self-harm with antidepressants
